Avene Cicalfate+ Repairing Protective Cream

Avène Cicalfate+ Repairing Protective Cream is a dermatologist-developed, clinically validated multi-purpose skin barrier repair cream from Eau Thermale Avène, France’s most trusted dermo-cosmetic brand for sensitive and fragile skin. The Cicalfate+ range is Avène’s iconic skin repair line, long recommended by dermatologists, paediatricians, and gynaecologists for the soothing and recovery of compromised, irritated, and damaged skin across all ages — from newborns to adults. This rich, protective cream is designed for the widest possible range of everyday skin-SOS situations: dry and dehydrated skin, visible redness and irritation, minor cuts and scrapes, stitches and post-procedure recovery, sunburn, eczema flare-ups, nappy rash, cracked and chapped skin, perioral dryness, and external intimate area irritation. Clinically proven to visibly soothe and begin restoring damaged skin in just 48 hours, and to accelerate the natural skin repair process by 4 times compared to untreated skin. Entirely fragrance-free, alcohol-free, paraben-free, sulfate-free, and silicone-free — formulated to minimise all risk of allergic reactions and accepted by the National Eczema Association. Safe and gentle for infants, children, and adults. Made in France.

The formula is built around three synergistic active systems that work together to soothe, protect, purify, and restore compromised skin. [C⁺-Restore]™ — the patented postbiotic star active of the upgraded Cicalfate+ formula — is a ferment filtrate derived from Aquaphilus Dolomiae, a microorganism uniquely found in Avène Thermal Spring Water itself. This biotechnological postbiotic is rich in bioactive proteins and metabolites that directly stimulate epidermal repair mechanisms, promoting the regeneration of skin cells and the restoration of the skin barrier from within, while simultaneously preserving and supporting the skin’s own natural microbiome for a healthier recovery environment. Clinical data shows that [C⁺-Restore]™ accelerates epidermal re-epithelialisation 4 times faster than untreated skin. Arginine, an amino acid included alongside the postbiotic filtrate, contributes to the formula’s skin-conditioning and restorative support. Avène Thermal Spring Water — the brand’s founding dermatological signature, validated across over 150 clinical studies — forms the soothing aqueous base of the cream. This unique thermally sourced mineral water from the Hérault spring is clinically proven to calm, soften, and reduce skin reactivity and discomfort; it is the primary reason why Cicalfate+ can be safely applied even to the most fragile neonatal skin without risk of irritation. The Copper Sulfate and Zinc Sulfate antibacterial complex — the [C⁺-Restore]™ purifying component — works to create a hostile environment for bacteria at the skin surface, reducing the risk of secondary infection in damaged or open skin and helping maintain a clean, protected healing environment. Zinc Oxide adds additional mild anti-inflammatory and skin-protective properties while contributing to the cream’s overall barrier-forming function. The occlusive and emollient base — Caprylic/Capric Triglyceride, Mineral Oil (Paraffinum Liquidum), Hydrogenated Vegetable Oil, Beeswax (Cera Alba), and Microcrystalline Wax — creates the cream’s characteristic rich, nourishing texture that forms a semi-occlusive protective film over the skin surface. This breathable “dressing effect” physically shields the damaged or irritated area from external aggressors — friction, environmental irritants, moisture loss — while maintaining the optimal hydration and temperature conditions needed for skin repair. Glycerin is included as a humectant to attract and retain moisture within the skin, preventing further dehydration of fragile tissues. Propylene Glycol supports the even delivery and absorption of active ingredients throughout the formula. Polyglyceryl-2 Sesquiisostearate and PEG-22/Dodecyl Glycol Copolymer are the gentle emulsifying agents that stabilise the water-in-oil emulsion and give the cream its smooth, easy-spreading consistency.

• [C⁺-Restore]™ (Aquaphilus Dolomiae Ferment Filtrate) — patented postbiotic active clinically proven to accelerate skin repair by 4× and restore the skin barrier in 48 hours
• Copper Sulfate + Zinc Sulfate complex — antibacterial purifying system that reduces bacterial proliferation risk and supports a clean healing environment
• Avène Thermal Spring Water — clinically soothing and anti-irritating, calms discomfort and supports skin tolerance throughout the repair process
• Zinc Oxide — mild anti-inflammatory and protective agent that strengthens the barrier-forming effect of the formula
• Beeswax + Microcrystalline Wax + Hydrogenated Vegetable Oil — occlusive base that creates a breathable protective “dressing effect” over damaged skin
• Glycerin — humectant that retains moisture and prevents further dehydration of fragile or compromised skin
• Multi-purpose use: eczema, nappy rash, cuts & scrapes, sunburn, post-procedure, cracked skin, perioral & intimate area dryness, and daily sensitive skin moisture
• Fragrance-free | Alcohol-free | Paraben-free | Sulfate-free | Silicone-free | Non-comedogenic | Accepted by the National Eczema Association
• Safe for infants, children, and adults | By Avène (Pierre Fabre) | Made in France | 40ml

How To Use: Apply Cicalfate+ Repairing Protective Cream to the affected area on clean, dry skin, massaging gently with soft movements to avoid further irritation. Use once or twice daily, or as directed by your dermatologist or healthcare professional. For eczema-prone skin, apply a thin layer locally in addition to your regular emollient cream. For best results on minor everyday irritations, apply a compress of Avène Thermal Spring Water to the area beforehand. Can be used on the face, body, and external intimate areas. Do not expose the product to temperatures below 0°C. For external use only. Avoid contact with eyes. Keep out of reach of children.